1. Edgar Allen Poe's "The Cask of Amontillado"
This is a weird scene to stumble on in Fallout 4, but it all makes sense if you're an Edgar Allen Poe scholar. The skeletons, one with the Amontillado bottle and one chained up inside a wall, are references to the Poe short story, "The Cask of Amontillado," in which a man buries his friend alive. His murder takes the term "frenemy" to a whole new level. Bethesda decided to bring the literary work to life because Poe was a famous Boston native. What makes Poe's story so memorable is that the motive, not the crime, is the mystery, like how the motive behind your senseless annihilation of every living thing in sight remains a mystery to NPCs.
2. The Bar from Cheers
Fallout takes place in Boston so it makes sense that Bethesda would include the most famous landmark in Boston: the bar from Cheers. Not Faneuil Hall or John Adams's birthplace. Nope, a bar from a TV show that somehow existed in this parallel timeline.
Those two skeletons clutching each other as they died could only be Sam and Diane.
And here's everybody's favorite postal worker.
3. Happy Birthday Sweet Roll!
At the beginning of Fallout 3, you're given a sweet roll at your birthday party. This is when you're a child and you live in Vault 101 and your life is still relatively good. Immediately, your roll is (in most cases) snatched from your hands. Sure, you lose both of your parents in this game, but the loss of a small pastry was a huge blow to many players and remains a sore spot for them. That's why Bethesda made sure to include a bittersweet reunion between your sweet roll and you in the next installment.
Redditor Enreganzar found the word GURPS in a Fallout 4 terminal. What's so SPECIAL about the word GURPS? Hate to break it to you, but SPECIAL wasn't always called SPECIAL. Before Fallout was the series we know and love, it was to be a tabletop game published by Steven Jackson Games, and the early working title was "Vault 13: A GURPS Post-Nuclear Adventure." GURPS isn't only the sound you make after chugging Coke Zero, it's also the acronym for Generic Universal Role Playing System, a game-playing system with points-based character creation. When Steven Jackson Games pulled out of the project, however, the developers had to create SPECIAL to replace GURPS, which resulted in the Fallout character creation we use today.
5. Opie from Sons of Anarchy
This Fallout 4 terminal displays a description of an Opie that matches the character Opie from the TV show Sons of Anarchy, down to the trademark leather vest and wool cap. What's the connection between Sons of Anarchy and Fallout 4 (besides being two pieces of excellent media too violent to recommend to your parents)? Ron Perlman, the star of Son of Anarchy, was the narrator of previous Fallout installments and lent his voice as the newscaster who appears on your family's TV at the beginning of Fallout 4.